REFERENCES COVID19 CHALLENGE

SILVER NANO FLUID PRODUCT ANALYSIS – 2.2.1. UV-Vis – UV absorption spectrogram analysis shows the light, among all wavebands from UV to infrared, has resonant effect with water phase nanosilver particles. As different materials have different resonance spectra, the resonance spectrum can be effectively used to prove and analyze for silver material. As shown in Figure 2, the resonance point of water phase nanosilver is at 393 nm. (end) A study of Antibioactivity of Nano Silver Colloid and silver Ion Solution – In this study they are making Colloidal from ELECTRICAL SPARK DISCHARGEESD – and has interesting references to the effects of UV light on solution.

Antibacterial efficacy of colloidal silver alone and in combination with other antibiotics on isolates from
wound Infections Iroha, I. R 1, Esimone, C. O. 2 , Orji J. O. 1 and Imomoh, O. O. 1
1Department of Applied Microbiology Ebonyi state University Abakaliki, Nigeria.
2Department of Pharmaceutics, University of Nigeria, Nsukka, Nigeria.
Accepted 4 July, 2007
RESULTS AND DISCUSSIONS – The result in Table 1 shows that the test organisms were completely susceptible to the therapeutic effect of colloidal silver at both concentrations. This proves the works of their authors that colloidal silver is a wonder antibiotic that has the ability to destroy over 650 microorganisms at a very low concentration without having any deleterious effect in the body tissues (Becker, 1978)……Colloidal silver contains minute silver particles of the ranges of 0.001 microns which results in its overall increased surface area. It has been proposed that this increased surface area is responsible for its quick and fast penetration into the cell wall of bacteria. Colloidal silver works by inhibiting and disabling the oxygen metabolism enzyme bacteria which finally kills off the microbes in an incredibly short period of time (Duncan, 1993). ….Also, the rapid killing potential of colloidal agent is because minute silver was able to attach to cell receptors and inhibit microbial cellular reproduction and respiration by attacking the important prokaryotic enzymes involved in microbial cell metabolism and the result also revealed that the killing rate was not concentration – dependent (Lloyd and Zane, 1996). We therefore conclude that due to the low toxicity associated with colloidal silver and its high therapeutic activity against pathogenic microorganisms, it can be suggested as an alternative to antibiotics for chemotherapy. .(extract end)

ABC WORLD TODAY – Death table data Medical stuff ups: By some estimates, as many as 18,000 people die every year as a result of medical error, while 50,000 people suffer a permanent injury. But there is no systematic collection and linking treatment error data, so it is impossible to know for sure how many medical mistakes cause serious harm or death. Here’s Emily Bourke with the first of her series of special reports on patient safety. EMILY BOURKE: Some people believe there’s a silent epidemic of error in the Australian health system. LORRAINE LONG: I think it’s so difficult for people to believe that doctors make mistakes and the way it’s been handled is, well, let’s keep it quiet. ….In 1995, the landmark Quality in Australian Health Care Study found the rate of so-called adverse events was 16.6 per cent among hospital patients, accounting for around 18,000 deaths and 50,000 cases of permanent disability.…”I don’t see a reduction in medical error at all. I still see cover-ups, I still see the lengths health departments will go to smother things and destroy records. But the errors are just the same, I’m not seeing a reduction. see full report Posted Monday 10  June 2013 Lets hope it has improved since then

DEATH STATISTICS TABLEAustralia’s leading causes of death, 2018 -There were 158,493 registered deaths in Australia in 2018. This paper outlines the leading causes of those deaths with a particular focus on age and sex. The table below shows the top 20 leading causes of mortality for 2018 compared with 10 years ago (2009) and 5 years ago (2013). Key points include:

  • The leading cause of death was Ischaemic heart disease. The standardised death rate from Ischaemic heart disease has decreased by 22.4% since 2009, with declines in heart disease mortality observed now for more than 50 years.
  • Dementia, including Alzheimer’s disease, remained the second leading cause of death. Deaths due to dementia have increased by 68.6% since 2009.
  • Cerebrovascular diseases, Cancer of the trachea, bronchus and lung and Chronic lower respiratory diseases round out the top five leading causes of death.
  • The top five leading causes of death account for more than one-third of all registered deaths.
  • Influenza and pneumonia was the 12th leading cause of death. The number of influenza deaths is strongly linked to the severity of flu seasons and this can drive changes in ranking for this leading cause group.
  • Intentional self-harm was the 14th leading cause of death. It has the lowest median age at death among the top 20 leading causes, at 44.4 years of age.

DAILY CONFIRMED COVID 19 CASES AND DEATHS This is a great site for all kinds of data to keep track of. Worth checking out. Only if we end the pandemic everywhere can we end the pandemic anywhere. The entire world has the same goal: cases of COVID-19 need to go to zero. (end)

BRAZIL VERY SICK PATIENTS, NOT ENOUGH STAFF IN AMAZONAS Amazonas state, in the country’s northwest, has the highest mortality rate from COVID-19 in Brazil. In Manaus, the state capital, the situation in the hospitals has been devastating. “The four main hospitals in Manaus were all full and the hard-working medical teams were dealing with extremely sick patients, often arriving too late and too far gone to be saved,” says Dr Bart Janssens, MSF Emergency Coordinator who launched our response. “A high percentage of the patients going into intensive care units were dying; and large numbers of medical staff were falling sick.”  …..In Tefe, a town one and a half days’ boat journey up the Amazon river, the medical staff were confronting an even more challenging situation. “When I visited to assess the situation, the hospital management team were telling me that almost 100 per cent of their COVID-19 patients needing intensive care had died,” says Dr Janssens. “They did not have enough specialist staff to care for the very sick patients that were arriving at their door.” (end)

High rate of death from VENTILATORS Generally speaking, 40% to 50% of patients with severe respiratory distress die while on ventilators, experts say. But 80% or more of coronavirus patients placed on the machines in New York City have died, state and city officials say. The patients may have become too sick by the time they were put on the machines, some experts said. But ventilators can be damaging to a patient over time, as high-pressure oxygen is forced into the tiny air sacs in a patient’s lungs, they said. “One of the most important findings in the last few decades is that medical ventilation can worsen lung injury _ so we have to be careful how we use it,” Dr. Eddy Fan, an expert on respiratory treatment at Toronto General Hospital….. Now last resort, other methods tried first – A few weeks ago in New York City, coronavirus patients who came in quite sick were routinely placed on ventilators, said Dr. Joseph Habboushe, an emergency medicine doctor who works in Manhattan hospitals. But increasingly, physicians are trying other measures first. One is having patients lie in different positions _ including on their stomachs _ to allow different parts of the lung to aerate better. Another is giving patients more oxygen through nose tubes or other devices. Some doctors are experimenting with adding nitric oxide to the mix, to help improve blood flow and oxygen to the least damaged parts of the lungs.

Inhibition of A/Human/Hubei/3/2005 (H3N2) influenza virus infection by silver nanoparticles in vitro and in vivoConclusion In this study, we used H3N2 IFV as a virus model to investigate the inhibitory activity of AgNPs (Silver Nano Particles-ed) against the influenza virus by performing a series of assays in vitro (MTT, hemagglutinin, flow cytometry, immunofluorescence, and TEM) and in vivo (an IFV-infected mouse model). In vitro, AgNPs significantly protected cells against viral infection by increasing their live viability and protecting against CPEs, inhibiting growth of the virus, and decreasing the cellular apoptosis induced by H3N2 IFV. AgNPs interacted with viral particles and destroyed their morphologic structures in a time-dependent manner. In addition, intranasal AgNP administration significantly enhanced survival in mice, prevented virus growth in their lungs, inhibited the development of pathologic lung lesions, and had a marked survival benefit on secondary passage. Taken together, the results indicate that AgNPs have promising antiviral activity against H3N2 IFV through multiple mechanisms, demonstrating that development of optimized AgNPs and further investigation of their relevant antiviral mechanisms will be critical for controlling influenza outbreaks.

Silver nanoparticles as potential antiviral agentsAbstract excerpt: Virus infections pose significant global health challenges, especially in view of the fact that the emergence of resistant viral strains and the adverse side effects associated with prolonged use continue to slow down the application of effective antiviral therapies. This makes imperative the need for the development of safe and potent alternatives to conventional antiviral drugs. In the present scenario, nanoscale materials have emerged as novel antiviral agents for the possibilities offered by their unique chemical and physical properties….The use of metal nanoparticles provides an interesting opportunity for novel antiviral therapies. Since metals may attack a broad range of targets in the virus there is a lower possibility to develop resistance as compared to conventional antivirals. …

Metal nanoparticles: The protective nanoshield against virus infection ABSTRACT: Re-emergence of resistance in different pathogens including viruses are the major cause of human disease and death, which is posing a serious challenge to the medical, pharmaceutical and biotechnological sectors. Though many efforts have been made to develop drug and vaccines against re-emerging viruses, researchers are continuously engaged in the development of novel, cheap and broad-spectrum antiviral agents, not only to fight against viruses but also to act as a protective shield against pathogens attack. Current advancement in nanotechnology provides a novel platform for the development of potential and effective agents by modifying the materials at nanolevel with remarkable physicochemical properties, high surface area to volume ratio and increased reactivity. Among metal nanoparticles, silver nanoparticles have strong antibacterial, antifungal and antiviral potential to boost the host immunity against pathogen attack. Nevertheless, the interaction of silver nanoparticles with viruses is a largely unexplored field. The present review discusses antiviral activity of the metal nanoparticles, especially the mechanism of action of silver nanoparticles, against different viruses such HSV, HIV, HBV, MPV, RSV, etc.

We do sell COLLOIDAL SILVER GENERATORS here and it is great fun making your own at virtually no cost but if you don’t feel you are up to it then have a look at Remo Colloidal Silver. I have a report that it was used as part of a TREATMENT which showed a very rapid recovery which amazed doctors. I understand they are doing more cases to see if the performance is consistent. We look forward to hearing more on this one.

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